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Guide: 5 Influential NFT Artists of 2021

Updated: May 22, 2025
Published: Jan 17, 2022
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In 2021, the NFT space exploded, pushing the boundaries of art. Below, we take a look at some of the most influential artists in the NFT space.

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But first, if you don't already know, NFT stands for non fungible token. Fungible means that things are interchangeable (any one pound coin has the same value as any other pound coin in the UK). Non-fungible refers to items that are of the same class but are unique, like houses or kittens. In the same manner, NFTs are unique digital tokens that represent ownership of a digital asset, which in some cases is linked to a physical item such as a watch or a piece of art.

Now, let's look at some of the hottest NFT artists. 

1. All-Seeing Seneca 

NFT artist, All Seeing Seneca is recognised by Sotheby’s as the Bored Ape Yacht Club’s official artist. Since their launch, more than $1 billion in sales have been attributed to the BAYC collection.

All-Seeing Seneca 

The artist has recently released a new series of NFTs at Dfinity’s Iconoclast event at Art Basel in Miami.

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2. Justin Aversano

Total artwork value: $2,931,833.76

Justin Aversano's Twin Flames collection has been bought by the likes of Snoop Dogg and Gary Vaynerchuk.

The collection contains photos of 100 sets of twins. One piece from the collection sold for $1.1 million at Christie’s in October.

Justin Aversano

3. Beeple

Total artwork value: $173,430,074.67 (52,300.357 ETH)

Mike “Beeple” Winklemann's “EVERYDAYS: THE FIRST 5000 DAYS,” a collection of digital artwork created over 13 years, sold for an eye-watering $69.3 million at Christie’s. Beeple instantly became one of the most valuable and influential NFT artists.

HUMAN ONE a physical piece of artwork described as a “kinetic video sculpture,” sold for $29 million at Christie’s.

Beeple

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4. Pak 

Total artwork value: $283,626,925.17

Pak is known for his minimalist, monochrome geometric art. His experimental piece, Merge, sold for $91.8 million in late 2021.

Pak

5. Tyler Hobbs

Total artwork value: $127,171,272.75

Tyler Hobbs is a visual NFT artist specialising in generative design, programming, drawing, and painting. His Incomplete Control piece sold for $228,578.00 (67.667 ETH).

Tyler Hobbs

Want to read more about NFTs? Click here to discover the top-selling NFTs of all time. 

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